How to Bake Preheat oven to 375 degrees. In skillet, cook beef over medium-high heat until thoroughly cooked. Mix together the cream of mushroom soup, frozen vegetables, garlic powder, ground beef and some salt and pepper in a bowl. Fill two oven safe mugs three-quarters of the way up with the pot pie fililng and top each with one biscuit. Bake until the biscuits are golden brown, 35 to 40 minutes. Enjoy!